Environmental hazard testing of nanobiomaterials

#1 by Lesley , Thu Dec 17, 2020 4:21 pm

M. J. B. Amorim, M. L. Fernández-Cruz, K. Hund-Rinke & J. J. Scott-Fordsmand
Environmental Sciences Europe volume 32, Article number: 101 (2020)


The European Medicines Agency (EMA) regards the potential risks of human medicinal products to the environment and their impacts are assessed, as well as management to limit this impact. Hazard assessment of novel materials, which differ from conventional chemicals, e.g. nanobiomaterials, poses testing challenges and represents a work-in-progress with much focus on the optimization of required methodologies. For this work-in-progress, we here highlight where changes/updates are required in relation to the main elements for international testing based on OECD guidelines, supported by knowledge from the nanotoxicity area. The outline describes two major sections, nanobiomaterials and environmental hazards, including its challenges and learned lessons, with recommendations for implementation in OECD guidelines. Finally, the way forward via a testing strategy is described.

Full paper available here: https://enveurope.springeropen.com/artic...302-020-00369-8

Posts: 38
Date registered 12.18.2019

Last edited 12.17.2020 | Top


In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models-A Perspective
The Right Stuff: On the Future of Nanotoxicology

Xobor Create your own Forum with Xobor